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Diagnosis

November 23rd, 2012

Sorologia laboratory the diagnosis is carried through through the detention of IgG, IgM, IgA and IgE for some sorolgicos tests in the first months: – Sabin Feldman? examination standard for toxoplasmose, detects IgG, but, for the complexity, it is of restricted use; – ELISA with capture of IgM? bigger sensitivity and especificidade; – ELISA with capture of IgA; – ISAGA? reaction of aglutinao for imunoabsoro? bigger sensitivity and especificidade in the detention of IgM, IgA and IgE that the ELISA; The IgG, initially, cannot be identified as of the proper patient, since the maternal antibodies pass through the placenta, having to be made a curve of the headings of IgG in the first months that, in case that they increase, indicate the infection of the RN. If the sorologia to suggest infection congenital, the treatment will be initiated. PCR? in amniotic liquid, blood and lquor. Lquor – Pleocitose; – Hiperproteinorraquia. Hemograma. Tests of heptica function.

Image – Ultrassonografia; – Cerebral Cat scan? multiple injuries, hipodensas with reinforcement ring; – Magnetic Resonance? examination standard. These examinations are used for detention of neurological injuries. Neurological, auditory and oftalmolgica evaluation. Treatment the precocious treatment leads to the cure of the manifestations and hinders sequelas, therefore, it must be managed same in assintomticos RN. Medication Pirimetamina Sulfadiazina Acid Espiramicina folnico Project symptomatic vInfeco – Pirimetamina – 2 mg/kg/dia of 12/12h, during 2 the 4 days; 1 mg/kg/dia during 6 months; to follow, 1 mg/kg 3x/semana up to 1 year. – Sulfadiazina? 100 mg/kg/dia of 12/12h, during 1 year. – Acid folnico? 5 the 10 mg? 3x/semana. In presence of liquricas alterations, to add Prednisona in dose of 1 mg/kg/dia of 12/12 h while to persist the alterations with gradual withdrawal. assintomtica vInfeco – Pirimetamina + Sulfaziazina + Acid folnico (doses above)? during 6 months and, to follow: Alternated monthly cycles – during more 6 months: – Pirimetamina + Sulfadiazina + Acid folnico (doses above) – Espiramicina? 100 mg/kg/dia of 12/12h vInfeco suspicion – Pirimetamina + Sulfadiazina during 1 month and to reevaluate the diagnosis.

Alzheimer

November 5th, 2012

In accordance with Cotran 2000, the main cerebral occurrences in each phase are: In the initial phase, the person is conscientious, perceives something wrong with its recent memory, has difficulty in learning and to hold back information and also she happens in the reduction of the learning capacity, thought and planning. In the intermediate phase, the patient already is not capable to learn and to hold back new information, affecting says and understanding to it of speech, perception of the body in relation to objects to its redor, causing object slips, falls, etc. In the final phase, the patient is not capable to walk, presenting incontinence, is in the stream bed and it does not say more. Most of the cortex seriously is damaged. The brain shrinks very in function of the death of cells in all the agency.

The people lose the capacity of if communicating, recognizing the dear family and same people and to take care of of itself. In the made specific examinations in patients with the evil of Alzheimer, she is possible to observe a changeable degree of cortical atrophy with widening of the cerebral ridges, being more evident in the wolves frontals, secular and parietais. The number of neurofibrilas interlaced, what it characterizes the degeneration to neurofibrilar and of senile plates, has some relation with the degree and the duration of the dementia (COTRAN, 2000). It has two categories of cerebral injuries, in one of them, the neurons show great plates of a called protein beta-amyloid, that it has toxic effect on the cells. In the other aspect, the neurons if in essential parts of its internal structure, the micron tbulos, that are twisted and confusions harming the functioning of these cells.

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