These glycoproteins if bind the receivers, particularly in the cells of Sertoli and Leydig. Its action occurs through quinases dependents of AMPc, who regulate the events intracellular. The FSH regulates the number and the activity of the cells of Sertoli, promotes gens for the vital protein synthesis, as carreadoras proteins of tiamina and transferrina and regulates the production of andrognios. The inibina and the activina are produced in the testicules and regulate the activity of the FSH through feedback and parcrina action. The inibina controls the production of andrognios and inhibits the FSH secretion.
The activina stimulates FSH secretion and can regulate another activity. The folistatina can modulate the effect of the activina and the folistatina can be involved in the development to folicular (RUTZ et al, 2007).